Featured Abstract: Development of membrane fusion engineered extracellular vesicles as antigen presentation carriers to improve the efficacy of HER2 antibody-drug conjugates
Location: Plenary - Hall C
Presenting Author: Shili Yao, n/a – School of Materials Science and Engineering, Faculty of Medicine, Tianjin University
Disease and therapy
Thursday, Apr 24th
10:30 – 11:00 CET
OT01.0 - Liquid Biopsy for CNS Tumors Using Tumor-secreted EVs
Location: Strauss 2
Presenter: Franz Lennard. Ricklefs – 7. Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Disease and therapy
Thursday, Apr 24th
11:00 – 11:15 CET
OT01.1 - Longitudinal monitoring of glioblastoma sEV evolution using a nanodiagnostic to detect emergence of glioma stem cells driving recurrent disease
Location: Strauss 2
Presenting Author: Zhen Zhang, n/a – The University of Queensland Australian Institute for Bioengineering and Nanotechnology
Disease and therapy
Thursday, Apr 24th
11:15 – 11:30 CET
OT01.2 - From challenge to opportunity: a methodology to measure reproducible EV concentrations
OT01.3 - Plasma extracellular vesicle-associated protease activity as a technically robust functional biomarker for uveal melanoma treatment response
Location: Strauss 2
Presenting Author: Jan Van Deun, PhD – Universitätsklinikum Erlangen
Disease and therapy
Thursday, Apr 24th
11:45 – 12:00 CET
OT01.4 - Unveiling neuroblastoma: characterizing the proteome and surface markers of extracellular vesicle to discover new biomarkers and elucidate premetastatic niche formation
Location: Strauss 2
Presenting Author: Martin Auber, n/a – Charité – University Medicine Berlin
Disease and therapy
Thursday, Apr 24th
14:30 – 15:00 CET
OT05.0 - MSC-EVs: Unlocking Clinical Potential and Overcoming Translational Challenges
Location: Strauss 2
Presenter: Bernd Giebel, Prof – Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
Disease and therapy
Thursday, Apr 24th
15:00 – 15:15 CET
OT05.1 - Dual-function extracellular vesicles for mRNA and enzyme co-delivery in Fabry disease therapy
Location: Strauss 2
Presenting Author: Sin-Yu Chen, n/a – Institute of Biopharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Disease and therapy
Thursday, Apr 24th
15:15 – 15:30 CET
OT05.2 - Enhanced delivery of RNA therapeutics via extracellular vesicles for targeted treatment of peritoneal and lung metastases
Location: Strauss 2
Presenting Author: Tram TT Nguyen, n/a – Yong Loo Lin School of Medicine, National University of Singapore
Disease and therapy
Thursday, Apr 24th
15:30 – 15:45 CET
OT05.3 - RNA-based therapies by red blood cell-derived extracellular vesicle mimetics: a new platform for the development of easily translatable and scalable therapeutics for chronic and metabolic diseases
Location: Strauss 2
Presenting Author: Sara Biagiotti – Department of Biomolecular Sciences, University of Urbino Carlo Bo
Disease and therapy
Thursday, Apr 24th
15:45 – 16:00 CET
OT05.4 - An engineered siRNA backbone improves siRNA delivery via extracellular vesicles
OF09.1 - Classical Ly6C^high monocytes play a critical role in mediating neuroprotection by mesenchymal stromal cell-derived small extracellular vesicles after ischemic stroke in mice
Location: Lehar 3-4
Presenting Author: Chen Wang, n/a – Department of Neurology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
Disease and therapy
Friday, Apr 25th
09:15 – 09:30 CET
OF09.2 - The effect of trimeric superoxide dismutase 1 on EVs in ALS
Location: Lehar 3-4
Presenting Author: Brianna Hnath, n/a – Penn State University College of Medicine
Disease and therapy
Friday, Apr 25th
09:30 – 09:45 CET
OF09.3 - Mechanically activated extracellular vesicles regulate angiogenesis for bone repair at different stages of the osteogenic lineage
OF09.4 - Recurrent Intranasal Administrations of Neural Stem Cell-Derived EVs Restrain Neuroinflammation and Maintain Better Cognitive function for Extended Periods in a Model of Alzheimer’s Disease
Location: Lehar 3-4
Presenting Author: Ashok K. Shetty, n/a (he/him/his) – Institute for Regenerative Medicine, Dept of Cell Biology and Genetics, Texas A&M University College of Medicine
Disease and therapy
Friday, Apr 25th
11:30 – 11:45 CET
Featured Abstract: Clinical trial: First-in-Human Intracochlear Application of Vesicle-Enriched Secretome Fractions (ESCRT)
Presenting Author: Athanasia Warnecke – Department of Otorhinolaryngology, Head and Neck Surgery, Hannover Medical School, Hannover, Germany
Disease and therapy
Friday, Apr 25th
14:30 – 15:00 CET
OF13.0 - Harnessing circulating tumor extracellular vesicles for longitudinal monitoring of cancer evolution and therapeutic response in Prostate Cancer
Location: Strauss 2
Presenter: Irene Casanova Salas – Vall d’Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus
Disease and therapy
Friday, Apr 25th
15:00 – 15:15 CET
OF13.1 - In vitro characterization of vesicles released by prostate cancer cells dictate PSMA/STEAP1-positive large-EVs as targets to immunocapture tumor-derived EVs ex vivo
OF13.2 - A novel platform for isolating brain cell-specific extracellular vesicles to profile the cellular environment in multiple pathologies of the brain
Location: Strauss 2
Presenting Author: Richard Lobb – The University of Queensland
Disease and therapy
Friday, Apr 25th
15:30 – 15:45 CET
OF13.3 - Detection and monitoring of prostate cancer using activity-based biomarkers from plasma extracellular vesicles
Location: Strauss 2
Presenting Author: Cuno Laurin Lange, n/a – Friedrich-Alexander-Universität Erlangen-Nürnberg, Department of Dermatology, Uniklinikum Erlangen
Disease and therapy
Friday, Apr 25th
15:45 – 16:00 CET
OF13.4 - Circulating extracellular vesicle isomiR networks to predict therapy response in patients with Multiple Myeloma
OS20.2 - Regulation of parasite virulence by extracellular vesicles during malaria infections
Location: Strauss 2
Presenting Author: Pierre-Yves Mantel, n/a – CK-CARE AG - Center for Allergy Research and Education
Disease and therapy
Saturday, Apr 26th
09:30 – 09:45 CET
OS20.3 - Modulation of cancer EVs secretion for improved immunotherapy outcomes in pancreatic cancer
Location: Strauss 2
Presenting Author: Carolina Dias, n/a – i3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal; FMUP – Faculdade de Medicina, Universidade do Porto, Porto, Portugal
Disease and therapy
Saturday, Apr 26th
09:45 – 10:00 CET
OS20.4 - Development of in vivo genome editing technology using plant-derived extracellular vesicles as drug delivery carriers
OS21.0 - EVs in Immune Suppression and Tumor Progression
Location: Strauss 2
Presenter: Wei Guo, n/a – University of Pennsylvania
Disease and therapy
Saturday, Apr 26th
15:00 – 15:15 CET
OS21.1 - A CD21 and phosphatidylserine-targeting fusion protein binds extracellular vesicles, targets them to B cells and potentiates their T-cell immunogenicity
OS21.2 - Targeted exosomal delivery of PD-L1 siRNA in lung tumor immunotherapy
Location: Strauss 2
Presenting Author: Farrukh Aqil (he/him/his) – Brown Cancer Center and Department of Medicine, University of Louisville, Louisville, KY 40202, USA.
Disease and therapy
Saturday, Apr 26th
15:30 – 15:45 CET
OS21.3 - Mechanisms and functions of CSF1 association to extracellular vesicles in anti-tumor immune responses
Location: Strauss 2
Presenting Author: Clotilde Thery – Institut Curie Research center, INSERM U932, PSL Research University, Paris, France
Disease and therapy
Saturday, Apr 26th
15:45 – 16:00 CET
OS21.4 - Distinct role of large oncosomes in modulating bone marrow microenvironment and promoting metastasis through immune reprogramming in cancer progression
Presenting Author: Jianlong Li, n/a – Southern Medical University
Disease and therapy
Sunday, Apr 27th
09:30 – 09:45 CET
LB01.5 - Blood cell-derived extracellular vesicles induce a pro-inflammatory phenotype in tubular epithelial cells of proliferative Lupus Nephritis patients
Location: Lehar 3-4
Presenting Author: Hilal Nur Sensoy, n/a – Department of Pathology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
Disease and therapy
Sunday, Apr 27th
09:45 – 10:00 CET
LB01.6 - Circulating extracellular vesicles-containing P.gingivalis OMVs from periodontitis patients trigger the release of inflammatory markers and the amyloid-ß peptide
Location: Lehar 3-4
Presenting Author: Charles Ramassamy, n/a – INRS-Centre Armand-Frappier Santé-Biotechnologie
