Full Schedule

09:45 – 10:00 CET

Featured Abstract: Non-lytic and active emission of cellular fragments carrying whole genome DNA during cancer cell migration

Presenting Author: – Cancer Research Program, Research Institute of the McGill University Health Centre, Montreal, QC, Canada

Senior Author: – Research Institute of the McGill University Health Centre

EV sources and basic biology

11:00 – 11:15 CET

Extracellular Vesicle Online Knowledge Explorer (EVOKE) - A guiding tool for the selection of extracellular vesicles preparation methods

Presenting Author: – Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, Ghent, Belgium; Cancer Research Institute Ghent, Ghent, Belgium. Electronic address: an.hendrix@ugent.be.

First Author: – Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Ghent University, Ghent, Belgium; Cancer Research Institute Ghent, Ghent, Belgium. Electronic address: an.hendrix@ugent.be.

Co-Author: – Laboratory of Experimental Cancer Research, Ghent University, Ghent, Belgium

Senior Author: – Laboratory of Experimental Cancer Research, Ghent University, Ghent, Belgium

Technologies and methods

11:15 – 11:30 CET

Selective enrichment of circulating cardiac-derived extracellular vesicles for disease monitoring

Presenting Author: – Mayo Clinic

First Author: – Mayo Clinic

Co-Author: – Mayo Clinic

Senior Author: – Mayo Clinic

Technologies and methods

11:30 – 11:45 CET

NANOSPACER: Nanofluidic sizing of extracellular vesicles and biomacromolecules in solution

Presenting Author: – UiT The Arctic University of Norway

First Author: – UiT The Arctic University of Norway

Technologies and methods

11:45 – 12:00 CET

Targeted isolation of prostate-derived EVs enhances the detection of tumor-specific markers for cancer diagnosis

Presenting Author: – Mayo Clinic

Co-Author: – University of Nebraska at Omaha

Co-Author: – Alfaisal University

Co-Senior Author: – University of Nebraska at Omaha

Senior Author: – Mayo Clinic

Technologies and methods

11:00 – 11:15 CET

Longitudinal monitoring of glioblastoma sEV evolution using a nanodiagnostic to detect emergence of glioma stem cells driving recurrent disease

Presenting Author: – The University of Queensland Australian Institute for Bioengineering and Nanotechnology

Co-First Author: – The University of Queensland

Co-Senior Author: – The University of Queensland

Disease and therapy

11:15 – 11:30 CET

From challenge to opportunity: a methodology to measure reproducible EV concentrations

Presenting Author: – Amsterdam UMC, University of Amsterdam

Co-Author: – Amsterdam UMC, University of Amsterdam

Co-Senior Author: – Laboratory of Experimental Clinical Chemistry, Amsterdam UMC

Senior Author: – Laboratory of Experimental Clinical Chemistry, Amsterdam UMC

Disease and therapy

11:30 – 11:45 CET

Plasma extracellular vesicle-associated protease activity as a technically robust functional biomarker for uveal melanoma treatment response

Presenting Author: – Universitätsklinikum Erlangen, University of Erlangen, FAU

First Author: – Universitätsklinikum Erlangen, University of Erlangen, FAU

Senior Author: – Universitätsklinikum Erlangen, University of Erlangen, FAU

Co-Author: – Universitätsklinikum Erlangen

Co-Author: – Universitätsklinikum Erlangen, University of Erlangen, FAU

Co-Author: – Universitätsklinikum Erlangen

Disease and therapy

11:45 – 12:00 CET

Unveiling neuroblastoma: characterizing the proteome and surface markers of extracellular vesicle to discover new biomarkers and elucidate premetastatic niche formation

Presenting Author: – Charité – University Medicine Berlin

First Author: – Charité – University Medicine Berlin

Co-Author: – Department of Pediatric Oncology and Hematology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität Berlin, Augustenburger Platz 1, 13353 Berlin, Germany

Co-Author: – German Rheumatology Research Center Berlin – A Leibniz Institute, Berlin, Germany

Co-Author: – Core Unit Proteomics, Berlin Institute of Health at Charité – Universitätsmedizin Berlin and Max-Delbrück- Center for Molecular Medicine, Berlin, Germany

Co-Author: – Department of Pediatric Endocrinology and Diabetology, Charité – Universitätsmedizin Berlin, Berlin, Germany

Co-Author: – Department of Pediatric Oncology and Hematology, University Hospital Tübingen, Tübingen, Germany

Co-Author: – Department of Pediatric Oncology and Hematology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität Berlin, Augustenburger Platz 1, 13353 Berlin, Germany

Co-Author: – German Rheumatology Research Center Berlin – A Leibniz Institute, Berlin, Germany

Co-Author: – Core Unit Proteomics, Berlin Institute of Health at Charité – Universitätsmedizin Berlin and Max-Delbrück- Center for Molecular Medicine, Berlin, Germany

Co-Author: – Department of Pediatric Oncology and Hematology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität Berlin, Augustenburger Platz 1, 13353 Berlin, Germany

Co-Author: – Integrative Vascular Biology Laboratory, Max Delbrück Center (MDC) for Molecular Medicine in the Helmholtz Association, Berlin, Germany

Disease and therapy

11:00 – 11:15 CET

“Proteomic and Lipidomic Insights into Toxoplasma gondii Extracellular Vesicles"

Presenting Author: – university of veterinary medicine of Vienna

Co-Author: – Department of Animal and Veterinary Sciences, Aarhus University, Denmark

Senior Author: – university of veterinary medicine of Vienna

EV sources and basic biology

11:15 – 11:30 CET

Endothelial Colony-Forming Cell-Derived Extracellular Vesicles Mitigate Immune and Cardiac Dysfunction in a Sepsis Model

Presenting Author: – Department of Genetics Cell and Immunobiology

Co-Author: – Department of Genetics, Cell- and Immunobiology

Co-Author: – Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary; Center for Pharmacology and Drug Research & Development, Semmelweis University, Budapest, Hungary

Co-Author: – Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary; Center for Pharmacology and Drug Research & Development, Semmelweis University, Budapest, Hungary; Pharmahungary Group, Szeged, Hungary

Co-Author: – Department of Genetics, Cell- and Immunobiology

Senior Author: – Semmelweis University, Department of Genetics, Cell- and Immunobiology; HUN-REN-SU Translational Extracellular Vesicle Research Group; HCEMM-SU Extracellular Vesicle Research Group

Senior Author: – Department of Genetics, Cell- and Immunobiology

Physiology and pathology

11:30 – 11:45 CET

Translocation and implication for disease pathogenesis of bacterial extracellular vesicles from gut commensal pathobiont Klebsiella pneumoniae in distant organs

First Author: – TOKAI University School of Medicine

Co-First Author: – Keio University Faculty of Pharmacy

Co-Author: – TOKAI University School of Medicine

Co-Author: – Department of Molecular Cellular Medicine, Tokyo Medical University Institute of Medical Science

Presenting Author: – TOKAI University School of Medicine

Physiology and pathology

11:45 – 12:00 CET

Single-cell RNA-Seq revealed that Legionella pneumophila-derived extracellular vesicles reprogram host macrophages to facilitate pathogen survival and spread

Presenting Author: – The Hong Kong Polytechnic University

Senior Author: – The Hong Kong Polytechnic University

Physiology and pathology

11:00 – 11:15 CET

RalA/B cooperate with EHD4 to shape multi-vesicular bodies for tumor EVs secretion

Presenting Author: – UMR_S1109 Tumor Biomechanics

First Author: – UMR_S1109 Tumor Biomechanics

Co-Author: – UMR_S1109 Tumor Biomechanics

Co-Author: – Plateforme Imagerie In Vitro, CNRS UAR 3156, Neuropôle, University of Strasbourg

Co-Author: – Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC)

Senior Author: – Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC)

Co-Author: – Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC)

Senior Author: – Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC)

Co-Author: – INSERM

Co-Author: – Etablissement francais du sang (EFS), INSERM

Co-Author: – Centre de Recherche en Cancérologie de Marseille (CRCM)

Co-Author: – Department of Biology, INSERM UMR_S1192, Protéomique Réponse Inflammatoire Spectrométrie de Masse-PRISM, Université de Lille

Co-Senior Author: – UMR_S1109 Tumor Biomechanics

EV sources and basic biology

11:15 – 11:30 CET

Phase separation induce the generation and cargo sorting of exosomes in multivesicular bodies

Presenting Author: – Tsinghua University

First Author: – Tsinghua University

Co-Author: – Tsinghua University

Co-Senior Author: – Tsinghua University

Senior Author: – Tsinghua University

EV sources and basic biology

11:30 – 11:45 CET

Amphiectosome release and “torn bag” secretion: a general exocytosis-independent mechanism for small extracellular vesicle release

Presenting Author: – Semmelweis University, Institute of Genetics, Cell- and Immunobiology

Co-First Author: – Semmelweis University, Institute of Genetics, Cell- and Immunobiology

Co-Senior Author: – Semmelweis University, Institute of Genetics, Cell- and Immunobiology

Co-First Author: – Semmelweis University, Department of Genetics, Cell- and Immunobiology

Co-Author: – Semmelweis University, Department of Genetics, Cell- and Immunobiology; HUN-REN-SU Translational Extracellular Vesicle Research Group

Co-Author: – Semmelweis University, Department of Genetics, Cell- and Immunobiology

Co-Author: – Department of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary

Co-Author: – Semmelweis University, Department of Genetics, Cell- and Immunobiology

Co-Author: – Semmelweis University, Department of Genetics, Cell- and Immunobiology, Nagyvárad tér 4. 1089 Budapest, Hungary;

Co-Author: – Laboratory of Neuroimmunology, HUN-REN Institute of Experimental Medicine

Co-Author: – Eötvös Loránd University, Department of Anatomy, Cell and Developmental Biology,

Co-Author: – Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského

Co-Author: – Semmelweis University, Department of Genetics, Cell- and Immunobiology; HUN-REN–ELTE Research Group of Peptide Chemistry, Hungarian Research Network

Co-Author: – Semmelweis University, Department of Genetics, Cell- and Immunobiology

Senior Author: – Semmelweis University, Department of Genetics, Cell- and Immunobiology; HUN-REN-SU Translational Extracellular Vesicle Research Group; HCEMM-SU Extracellular Vesicle Research Group

EV sources and basic biology

11:45 – 12:00 CET

Systemic propagation of STING signaling via generation of large extracellular vesicles

Presenting Author: – California State University Long Beach

First Author: – California State University Long Beach

Co-Senior Author: – California State University Long Beach

Co-Author: – University of Washington

Senior Author: – University of Washington

EV sources and basic biology

15:00 – 15:15 CET

Stress-Induced Modifications in NPCE-Derived Extracellular Vesicle Lipidome and microRNA Content Alter Trabecular Meshwork Cell Function: Implications for Glaucoma Pathogenesis

Presenting Author: – Ben-Gurion University of the Negev,

Senior Author: – Ben-Gurion University of the Negev,

Co-Author: – Ben-Gurion University of the Negev,

Co-Author: – Indiana University

Co-Senior Author: – Ben-Gurion University of the Negev

EV sources and basic biology

15:15 – 15:30 CET

Deciphering the fate of tumor derived EVs within dendritic cells

Presenting Author: – Institut Curie Research center, INSERM U932, PSL Research University, Paris, France

Co-Senior Author: – Institut Curie Research center, INSERM U932, PSL Research University, Paris, France

Senior Author: – Institut Curie Research center, INSERM U932, PSL Research University, Paris, France

EV sources and basic biology

15:30 – 15:45 CET

Lipid fluidity regulates EV budding from the plasma membrane

First Author: – University of Denver

Co-Author: – University of Denver

Presenting Author: – Texas A&M University

Senior Author: – Texas A&M University

EV sources and basic biology

15:45 – 16:00 CET

Decoding de novo synthetized proteins in the polarized macrophage´s soluble and EV-enclosed secretomes and their uptake into fibroblasts

Co-First Author: – University Hospital Cologne and University of Cologne, Department of Pediatrics, Pulmonology and Allergology

Presenting Author: – Center for Physiology and Pharmacology (Institute of Vascular Biology and Thrombosis Research), Medical University of Vienna

Co-First Author: – Center for Physiology and Pharmacology (Institute of Vascular Biology and Thrombosis Research), Medical University of Vienna

Co-Senior Author: – Center for Physiology and Pharmacology (Institute of Vascular Biology and Thrombosis Research), Medical University of Vienna

Co-Author: – CECAD Research Center, Institute for Genetics, University of Cologne

Co-Author: – Department I of Internal Medicine, Faculty of Medicine, University of Cologne, University Hospital Cologne, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Center for Molecular Medicine Cologne, CECAD Center of Excellence on Cellular Stress Responses in Aging-Associated Diseases, Cologne, Germany

Co-Author: – University Hospital Cologne, Klink für Dermatologie und Venerologie

Co-Senior Author: – CECAD Research Center, Institute for Genetics, University of Cologne

EV sources and basic biology

15:00 – 15:15 CET

Dual-function extracellular vesicles for mRNA and enzyme co-delivery in Fabry disease therapy

Presenting Author: – Institute of Biopharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.

First Author: – Institute of Biopharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.

Senior Author: – Institute of Biopharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.

Disease and therapy

15:15 – 15:30 CET

Enhanced delivery of RNA therapeutics via extracellular vesicles for targeted treatment of peritoneal and lung metastases

Presenting Author: – Yong Loo Lin School of Medicine, National University of Singapore

Co-Senior Author: – National University of Singapore

Disease and therapy

15:30 – 15:45 CET

RNA-based therapies by red blood cell-derived extracellular vesicle mimetics: a new platform for the development of easily translatable and scalable therapeutics for chronic and metabolic diseases

Presenting Author: – Department of Biomolecular Sciences, University of Urbino Carlo Bo

Co-Author: – Department of Biomolecular Sciences, University of Urbino Carlo Bo

Disease and therapy

15:45 – 16:00 CET

An engineered siRNA backbone improves siRNA delivery via extracellular vesicles

First Author: – University Medical Center Utrecht

Co-First Author: – University Medical Center Utrecht

Co-Author: – Utrecht University

Presenting Author: – UMC Utrecht

Senior Author: – UMC Utrecht

Disease and therapy

15:00 – 15:15 CET

Squeezable Hydrogel Microparticles for Single Extracellular Vesicle Protein Profiling

Presenting Author: – University of Pennsylvania

Senior Author: – University of Pennsylvania

Co-First Author: – University of Pennsylvania

Technologies and methods

15:15 – 15:30 CET

Single Extracellular VEsicle Nanoscopy-Universal Protocol (SEVEN-UP): accessible imaging platform for quantitative characterization of single extracellular vesicles

Co-First Author: – Beckman Research Institute, City of Hope

Co-Author: – Beckman Research Institute, City of Hope

Presenting Author: – Beckman Research Institute, City of Hope

Senior Author: – Beckman Research Institute, City of Hope

Technologies and methods

15:30 – 15:45 CET

Mapping single extracellular vesicle landscapes to dissect tumour heterogeneity and evolution of drug resistance in glioblastoma

Presenting Author: – Research Institute of McGill University Health Center (RI-MUHC)

First Author: – Research Institute of McGill University Health Center (RI-MUHC)

Co-Author: – Research Institute of the McGill UHC

Co-Author: – McGill University

Co-Author: – Research Institute of the McGill UHC

Co-Author: – McGill University

Co-Senior Author: – McGill University

Senior Author: – McGill University

Technologies and methods

15:45 – 16:00 CET

Single vesicle-resolved lipidomics of extracellular vesicles via mass spectrometry imaging to untangle the EV interactome in ovarian cancer

First Author: – University of California, Davis

Co-First Author: – University of California, Davis

Co-Senior Author: – University of California, Davis

Presenting Author: – University of California, Davis

Senior Author: – University of California, Davis

Technologies and methods

14:30 – 15:00 CET

Multidrug resistance transporter ABCG2 activity maintains stem cell quiescence by extracellular vesicle-mediated extraction of membrane microdomains.

Presenting Author: – Goethe University Frankfurt

Physiology and pathology

15:00 – 15:15 CET

Role of cardiomyocyte-derived extracellular vesicles in post-ischemic cardiac remodeling

Presenting Author: – Université Paris cité, INSERM U970, PARCC, Paris, France

Co-Author: – Institut Pasteur, Paris, France

Co-Author: – Polygon Therapeutics, Paris, France

Co-Author: – Université Paris cité, INSERM U970, PARCC, Paris, France

Senior Author: – Université Paris cité, INSERM U970, PARCC, Paris, France

Physiology and pathology

15:15 – 15:30 CET

Novel Insights into Extracellular Vesicle Trafficking in Cardiac Injury

First Author: – Texas A&M University

Co-Author: – Texas A&M University

Presenting Author: – Texas A&M University

Senior Author: – Texas A&M University

Physiology and pathology

15:30 – 15:45 CET

Podocyte exopher-formation in membranous nephropathy

Presenting Author: – Institute of Cellular and Integrative Physiology, University Medical Center Hamburg-Eppendorf, Hamburg

First Author: – Institute of Cellular and Integrative Physiology, University Medical Center Hamburg-Eppendorf, Hamburg

Co-Author: – Institute of Cellular and Integrative Physiology, University Medical Center Hamburg-Eppendorf, Hamburg

Co-Author: – Interfaculty Institute for Genetics and Functional Genomics, Greifswald, Germany

Co-Author: – Institute of Pathology, Nephropathology Section, University Medical Center Hamburg-Eppendorf, Germany

Co-Author: – Nephrology, Asklepios Klinikum Barmbek, Hamburg, Germany

Co-Author: – Institute of Neuroanatomy, Medical Faculty, University Bonn, Bonn, Germany

Co-Author: – Institute of Cellular and Integrative Physiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Senior Author: – Institute of Cellular and Integrative Physiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Physiology and pathology

15:45 – 16:00 CET

Intra-nephron cross talk through exosomes

First Author: – Universitätsklinikum Erlangen

Co-Author: – Universitätsklinikum Erlangen

Presenting Author: – Universitätsklinikum Erlangen

Physiology and pathology