Full Schedule

08:30 – 09:00 CET

OF09.0 - Decoding the Healing Dialogues

Location: Lehar 3-4

Presenter: – Indiana University

Disease and therapy

09:00 – 09:15 CET

OF09.1 - Classical Ly6C^high monocytes play a critical role in mediating neuroprotection by mesenchymal stromal cell-derived small extracellular vesicles after ischemic stroke in mice

Location: Lehar 3-4

Presenting Author: – Department of Neurology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

Disease and therapy

09:15 – 09:30 CET

OF09.2 - The effect of trimeric superoxide dismutase 1 on EVs in ALS

Location: Lehar 3-4

Presenting Author: – Penn State University College of Medicine

Disease and therapy

09:30 – 09:45 CET

OF09.3 - Mechanically activated extracellular vesicles regulate angiogenesis for bone repair at different stages of the osteogenic lineage

Location: Lehar 3-4

Presenting Author: – Trinity College Dublin

Disease and therapy

09:45 – 10:00 CET

OF09.4 - Recurrent Intranasal Administrations of Neural Stem Cell-Derived EVs Restrain Neuroinflammation and Maintain Better Cognitive function for Extended Periods in a Model of Alzheimer’s Disease

Location: Lehar 3-4

Presenting Author: – Institute for Regenerative Medicine, Dept of Cell Biology and Genetics, Texas A&M University College of Medicine

Disease and therapy

08:30 – 09:00 CET

OF10.0 - Modulating Protein Corona on EVs When They Are Born for Effortless Cell Targeting

Location: Strauss 2

Presenter: – University of Hong Kong, Hong Kong

EV sources and basic biology

09:00 – 09:15 CET

OF10.1 - Single-particle analysis reveals the presence of tRNA fragments on the surface of extracellular vesicles

Location: Strauss 2

Presenting Author: – Aarhus University

EV sources and basic biology

09:15 – 09:30 CET

OF10.2 - Chitosan oligosaccharides inhibit protein corona formation on extracellular vesicles to facilitate sepsis treatment

Location: Strauss 2

Presenting Author: – Institute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine

EV sources and basic biology

09:30 – 09:45 CET

OF10.3 - Tracking the extracellular vesicle biomolecular corona in physiological environments

Location: Strauss 2

Presenting Author: – University of Brescia

EV sources and basic biology

09:45 – 10:00 CET

OF10.4 - TGF-β-activated cancer-associated fibroblasts remodel the tumor microenvironment through extracellular vesicle surface-associated proteins

Location: Strauss 2

Presenting Author: – Leiden University Medical Center

EV sources and basic biology

08:30 – 09:00 CET

OF11.0 - The metastatic and systemic effects of tumor-derived EVPs

Location: Strauss 1

Presenter: – Weill Cornell Medicine

EV sources and basic biology

09:00 – 09:15 CET

OF11.1 - Targeting Rab27B-mediated extracellular vesicle release evokes DNA damage response in ER-positive breast cancer

Location: Strauss 1

Presenting Author: – Laboratory of Experimental Cancer Research, Ghent University, Ghent, Belgium

EV sources and basic biology

09:15 – 09:30 CET

OF11.2 - Extracellular vesicle-mediated release of beta-2 adrenergic receptor by prostate cancer cells and its impact on tumor microenvironment.

Location: Strauss 1

Presenting Author: – Oslo University Hospital

EV sources and basic biology

09:30 – 09:45 CET

OF11.3 - Delivery of melanoma cell-derived miR-92b-3p by extracellular vesicles promotes the formation of carcinoma-associated fibroblasts through the downregulation of PTEN

Location: Strauss 1

Presenting Author: – Department of Dermatology and Venereology, Martin-Luther-University Halle-Wittenberg

Physiology and pathology

09:45 – 10:00 CET

OF11.4 - Exploring the role of exercise-induced extracellular vesicles in breast cancer: mechanisms and implications

Location: Strauss 1

Presenting Author: – Latvian Biomedical Research and Study Centre

Physiology and pathology

08:30 – 09:00 CET

OF12.0 - EV Hybrids and Mimetics for cancer therapy: Challenges and Future Perspectives

Location: Lehar 1-2

Presenter: – National University of Singapore

Technologies and methods

09:00 – 09:15 CET

OF12.1 - Single-particle tracking analysis of extracellular vesicles, synthetic vesicles and hybrid vesicles for a deconvoluted understanding of uptake and transfection efficiency

Location: Lehar 1-2

Presenting Author: – Aarhus University

Technologies and methods

09:15 – 09:30 CET

OF12.2 - Comparative proteomics of extracellular vesicles and liposomes show cancer-related proteins and biomarkers

Location: Lehar 1-2

Presenting Author: – Cancer Research Program, Research Institute of the McGill University Health Centre

Technologies and methods

09:30 – 09:45 CET

OF12.3 - Synthetic extracellular vesicles: Differential effects of membrane and cytosolic proteins on physicochemical properties and functions

Location: Lehar 1-2

Presenting Author: – Cancer Research Program, Research Institute of the McGill University Health Centre, Montreal, QC, Canada

Technologies and methods

09:45 – 10:00 CET

OF12.4 - Stable anti-fouling nanospheres to standardize concentration measurements of extracellular vesicles

Location: Lehar 1-2

Presenting Author: – Amsterdam University Medical Center

Technologies and methods

10:00 – 10:30 CET

Coffee Break

Location: Hall C

10:30 – 11:15 CET

Plenary 2: The ESCRT machinery in biogenesis of intraluminal and extracellular vesicles
Chair: An Hendrix
Co-Chair: Ken Witwer

Location: Plenary - Hall C

Presenter:

11:15 – 11:30 CET

Featured Abstract: Development of a live-cell imaging assay to elucidate spatiotemporal dynamics of extracellular vesicle fusion with target cells

Location: Plenary - Hall C

Presenting Author: – Utrecht University

Technologies and methods

11:30 – 11:45 CET

Featured Abstract: Clinical trial: First-in-Human Intracochlear Application of Vesicle-Enriched Secretome Fractions (ESCRT)

Presenting Author: – Department of Otorhinolaryngology, Head and Neck Surgery, Hannover Medical School, Hannover, Germany

Disease and therapy

11:45 – 11:55 CET

Sponsor presentation: Beckman Coulter

Location: Plenary - Hall C

11:55 – 12:00 CET

Sponsor presentation: ONI

12:00 – 13:30 CET

Lunch break

Location: Hall C

12:30 – 13:30 CET

Sponsor lunch: ONI

Location: Stolz 2

12:30 – 13:30 CET

Poster Session 1 - Friday Session One Posters

12:30 – 13:30 CET

Sponsor lunch: Exokeryx

Location: Stolz 1

12:30 – 13:30 CET

Sponsor lunch: Stemcell Technologies

Location: Schubert 1-3

13:30 – 14:30 CET

Mixed Format: Key takeaways from the Scientific Reproducibility Task Forces

Location: Schubert 4-6

Moderator: – Laboratory of Experimental Clinical Chemistry, Amsterdam UMC

13:30 – 14:30 CET

Mixed Format: Trauma and EVs

Location: Press Center C

Moderator: – Ludwig Boltzmann Institute for Traumatology, the research center in cooperation with AUVA, Austria

Moderator: – Institute of Tendon and Bone Regeneration; Paracelsus Medical UniversityInstitute of Tendon and Bone Regeneration; Paracelsus Medical University

13:30 – 14:30 CET

Mixed Format: Clinical Application of EVs - Achievements and Roadblocks?

Location: Plenary - Hall C

Moderator: – Transfusion Medicine at SALK / Paracelsus Medizinische Privatuniversität Salzburg - Privatstiftung

Moderator: – Semmelweis University, Department of Genetics, Cell- and Immunobiology; HUN-REN-SU Translational Extracellular Vesicle Research Group; HCEMM-SU Extracellular Vesicle Research Group, Budapest, Hungary

13:30 – 14:30 CET

Mixed Format: SNEV Meet the EV-experts Session II: Analysis, Reproducibility and Application

Location: VIP C Lounge

Moderator: – Laboratory for extracellular vesicles research, Department of human genetics, KU Leuven, Leuven, Belgium

13:30 – 16:30 CET

Poster Switch (session 1 posters removed, session 2 posters installed)

14:30 – 15:00 CET

OF13.0 - Harnessing circulating tumor extracellular vesicles for longitudinal monitoring of cancer evolution and therapeutic response in Prostate Cancer

Location: Strauss 2

Presenter: – Vall d’Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus

Disease and therapy

15:00 – 15:15 CET

OF13.1 - In vitro characterization of vesicles released by prostate cancer cells dictate PSMA/STEAP1-positive large-EVs as targets to immunocapture tumor-derived EVs ex vivo

Location: Strauss 2

Presenting Author: – University of Trento

Disease and therapy

15:15 – 15:30 CET

OF13.2 - A novel platform for isolating brain cell-specific extracellular vesicles to profile the cellular environment in multiple pathologies of the brain

Location: Strauss 2

Presenting Author: – The University of Queensland

Disease and therapy

15:30 – 15:45 CET

OF13.3 - Detection and monitoring of prostate cancer using activity-based biomarkers from plasma extracellular vesicles

Location: Strauss 2

Presenting Author: – Friedrich-Alexander-Universität Erlangen-Nürnberg, Department of Dermatology, Uniklinikum Erlangen

Disease and therapy

15:45 – 16:00 CET

OF13.4 - Circulating extracellular vesicle isomiR networks to predict therapy response in patients with Multiple Myeloma

Location: Strauss 2

Presenting Author: – Amsterdam UMC - Cancer Center Amsterdam

Disease and therapy

14:30 – 15:00 CET

OF14.0 - They are not alone: EVs and viruses sharing and shaping the extracellular space

Location: Lehar 1-2

Presenter: – Institute of Virology, Philipps University Marburg, Marburg, Germany

EV sources and basic biology

15:00 – 15:15 CET

OF14.1 - Human Milk-derived Extracellular Vesicles Reduce NF-kB Pathway Activation and NLRP3 Inflammasome Formation in vitro and in vivo.

Location: Lehar 1-2

Presenting Author: – The University of Winnipeg

EV sources and basic biology

15:15 – 15:30 CET

OF14.2 - Mesenchymal stromal cells overexpressing hypoxia-inducible factor 1 alpha and notch 1 intracellular domain release small extracellular vesicles with potential for cardiac repair

Location: Lehar 1-2

Presenting Author: – Instituto de Investigación Sanitaria La Fe

EV sources and basic biology

15:30 – 15:45 CET

OF14.3 - Dual miRNA enriched MSC-sEV Formulation as a Novel Regenerative Modality to Enhance Skin and Hair Regeneration

Location: Lehar 1-2

Presenting Author: – AIIMS, New Delhi

EV sources and basic biology

15:45 – 16:00 CET

OF14.4 - ExRNA Atlas v3 map of extracellular RNA in human biofluids sheds light on the exRNA “dark matter” beyond previously annotated genomic regions

Location: Lehar 1-2

Presenting Author: – Department of Molecular and Human Genetics, Baylor College of Medicine

EV sources and basic biology

14:30 – 15:00 CET

OF15.0 - Building an infrastructure for sustainable reproducibility of EV research

Location: Strauss 1

Presenter: – Laboratory of Experimental Clinical Chemistry, Amsterdam UMC

Technologies and methods

15:00 – 15:15 CET

OF15.1 - Automated gating for reproducible measurements of extracellular vesicles by flow cytometry

Location: Strauss 1

Presenting Author: – University of Nebraska at Omaha

Technologies and methods

15:15 – 15:30 CET

OF15.2 - Mapping bacterial extracellular vesicle research: insights, best practices and knowledge gaps

Location: Strauss 1

Presenter: – Ghent University

Technologies and methods

15:30 – 15:45 CET

OF15.3 - Stripping the Adsorbed Protein Corona May Improve Immune Detection of EVs

Location: Strauss 1

Presenting Author: – Semmelweis University, Department of Genetics, Cell- and Immunobiology

Technologies and methods

15:45 – 16:00 CET

OF15.4 - EV Barcode: A Web Resource to Predict EV Source from EV cargo

Location: Strauss 1

Presenting Author: – La Trobe University

Technologies and methods

14:30 – 15:00 CET

OF16.0 - EVs and Lymphocytes: Mapping Their Interactions In Vivo

Location: Lehar 3-4

Presenter: – LMU Munich

Physiology and pathology

15:00 – 15:15 CET

OF16.1 - Filaggrin insufficiency leads to accumulation of anti-adhesive proteins associated with keratinocyte-derived sEVs which impacts their propensity for uptake by dendritic cells.

Location: Lehar 3-4

Presenting Author: – University of Gdańsk

Physiology and pathology

15:15 – 15:30 CET

OF16.2 - Plasma Extracellular Vesicles Control Neutrophil Inflammation via CD39/CD73-Mediated ATP Cleavage

Location: Lehar 3-4

Presenting Author: – Johns Hopkins University

Physiology and pathology

15:30 – 15:45 CET

OF16.3 - ESCRT-0-mediated fine-tuning of PD-L1 secretion via small extracellular vesicles

Location: Lehar 3-4

Presenting Author: – Wuhan University

EV sources and basic biology

15:45 – 16:00 CET

OF16.4 - When cellular couriers spark universal reactions: unveiling the consistent immunogenicity of diverse human EVs in primates

Location: Lehar 3-4

Presenting Author: – Department of Molecular and Comparative Pathobiology, Johns Hopkins Medicine, Baltimore, MD, USA

Physiology and pathology

16:00 – 16:30 CET

Coffee Break

16:30 – 17:30 CET

Poster Session 2 - Friday Session Two Posters

17:45 – 18:45 CET

Satellite Meeting: Annual Global EV Network Meeting

Location: Schubert 4-6

Moderator: – Semmelweis University, Department of Genetics, Cell- and Immunobiology; HUN-REN-SU Translational Extracellular Vesicle Research Group; HCEMM-SU Extracellular Vesicle Research Group, Budapest, Hungary

17:45 – 18:45 CET

Satellite Meeting: EV and host pathogen interaction

Location: VIP C Lounge

Moderator: – Departamento de Ciências Farmacêuticas, Unifesp, Diadema, SP, Brazil

17:45 – 19:15 CET

Satellite Meeting: Bacterial EVs: Basics and Beyond Task Force

Location: Stolz 1

Moderator: – University of Auckland, Auckland, New Zealand

17:45 – 19:15 CET

Satellite Meeting: EV exploitation in liquid biopsy/ISEV-ELBS Intersociety Working Group

Location: Strauss 1

Moderator: – Department of Cellular, Computational, and Integrative Biology (CIBIO), University of Trento, Trento, Italy

17:45 – 19:15 CET

Satellite Meeting: EVP FAIR-KID Task Force

Location: Schubert 1-3

Moderator: – Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States

17:45 – 19:15 CET

Satellite Meeting: Highlights of ASEV

Location: Lehar 3-4

Moderator: – Ludwig Boltzmann Institute for Traumatology, the research center in cooperation with AUVA, Vienna, Wein, Austria

17:45 – 19:15 CET

Satellite Meeting: Meet the Hurdle - EV Therapeutics and Regulations

Location: Lehar 1-2

Moderator: – Department of Transfusion Medicine, Salzburg University Hospital, Paracelsus Medical University, Salzburg

17:45 – 19:15 CET

Satellite Meeting: SNEV—EVs academic insertion: experiences from young PIs

Location: Strauss 2

Moderator: – Laboratory for extracellular vesicles research, Department of human genetics, KU Leuven, Leuven, Belgium