Full Schedule

08:30 – 09:00 CET

OS17.0 - EVs for Lung Repair and Drug Delivery

Location: Strauss 1

Presenter: – UNC-Chapel Hill & NC State University

Technologies and methods

09:00 – 09:15 CET

OS17.1 - Protein corona role in the targeting properties of extracellular vesicles for engineering therapeutic biomimetic nanoparticles

Location: Strauss 1

Presenting Author: – University of Zaragoza (Aragon Nanoscience and Materials Institute)

Technologies and methods

09:15 – 09:30 CET

OS17.2 - Targeting the tumor microenvironment: a click chemistry-based surface-functionalization method and a therapeutic-loading strategy for artificially produced erythrocyte-derived extracellular vesicles

Location: Strauss 1

Presenting Author: – University of Genova

Technologies and methods

09:30 – 09:45 CET

OS17.3 - Modulating binding affinity of aptamer-based loading constructs enhances EV-mediated CRISPR/Cas9 delivery

Location: Strauss 1

Presenting Author: – Pharmaceutics, UIPS

Technologies and methods

09:45 – 10:00 CET

OS17.4 - Engineering Extracellular Matrix-bound Nanovesicles Secreted by Human Brain Organoids with Different Regional Identity

Location: Strauss 1

Presenting Author: – Florida State University

EV sources and basic biology

08:30 – 09:00 CET

OS18.0 - EV-mediated Glia-Neuron Signaling: Enhancing Axonal Energy Metabolism and Synaptogenesis

Location: Lehar 3-4

Presenter: – National Institute of Neurological Disorders and Stroke (NINDS), NIH

Physiology and pathology

09:00 – 09:15 CET

OS18.1 - Alcohol-exposed hepatocyte-derived exosomes sensitize microglia to a pro-inflammatory phenotype via miRNA-122 transfer

Location: Lehar 3-4

Presenting Author: – Beth Israel Deaconess Medical Center & Harvard Medical School

EV sources and basic biology

09:15 – 09:30 CET

OS18.2 - APOE4/4 induced human microglia secrete extracellular vesicles enriched for proteins associated with immune response and proteasomal pathways

Location: Lehar 3-4

Presenting Author: – Derpartment of Neuroscience, Mayo Clinic, Jacksonville, FL, USA

Physiology and pathology

09:30 – 09:45 CET

OS18.3 - Brain pericytes: from origins to implications in cell-cell communication within the neurovascular unit through extracellular vesicles

Location: Lehar 3-4

Presenting Author: – Université d'Artois - LBHE

Physiology and pathology

09:45 – 10:00 CET

OS18.4 - APOE4 drives neuroinflammation and lipid dysbiosis in Alzheimer’s disease by modulating lipid compositions and cell adhesion molecules in brain-derived extracellular vesicles

Location: Lehar 3-4

Presenting Author: – Derpartment of Neuroscience, Mayo Clinic, Jacksonville, FL, USA

Physiology and pathology

08:30 – 09:00 CET

OS19.0 - Breaking Barriers: Microbial EVs at the Crossroad of Inflammation

Location: Lehar 1-2

Presenter: – UKER, Medizinische Klinik 1

EV sources and basic biology

09:00 – 09:15 CET

OS19.1 - Role of extracellular vesicles in placenta-brain dialogue during congenital human cytomegalovirus infection

Location: Lehar 1-2

Presenting Author: – INSERM - Toulouse 3 University

Physiology and pathology

09:15 – 09:30 CET

OS19.2 - Probiotic extracellular vesicles: Exploring their utility as a preventative and potential treatment approach for colorectal cancer-associated cachexia

Location: Lehar 1-2

Presenting Author: – La Trobe University

EV sources and basic biology

09:30 – 09:45 CET

OS19.3 - Bacterial Extracellular Vesicles as Protective Decoys: A Novel Mechanism of Resistance

Location: Lehar 1-2

Presenting Author: – Institute for Lung Research and Core Facility Flow Cytometry – Bacterial Vesicles, Philipps-University Marburg, Germany

EV sources and basic biology

09:45 – 10:00 CET

OS19.4 - From bacteria with love: Extracellular vesicles as intranasal postbiotics in allergy prevention and treatment

Location: Lehar 1-2

Presenting Author: – Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria

EV sources and basic biology

08:30 – 09:00 CET

OS20.0 - Clinical application of EV-based therapeutics

Location: Strauss 2

Presenter: – GMP Unit, Paracelsus Medical University Salzburg and Ludwig-Boltzmann Institute for Nanovesicular Precision Medicine

Disease and therapy

09:00 – 09:15 CET

OS20.1 - Therapeutic poxvirus triggers the secretion of extracellular vesicles with immunomodulatory anti-tumoral activity

Location: Strauss 2

Presenting Author: – UMR_S1109 Tumor Biomechanics / Transgene S.A.

Disease and therapy

09:15 – 09:30 CET

OS20.2 - Regulation of parasite virulence by extracellular vesicles during malaria infections

Location: Strauss 2

Presenting Author: – CK-CARE AG - Center for Allergy Research and Education

Disease and therapy

09:30 – 09:45 CET

OS20.3 - Modulation of cancer EVs secretion for improved immunotherapy outcomes in pancreatic cancer

Location: Strauss 2

Presenting Author: – i3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal; FMUP – Faculdade de Medicina, Universidade do Porto, Porto, Portugal

Disease and therapy

09:45 – 10:00 CET

OS20.4 - Development of in vivo genome editing technology using plant-derived extracellular vesicles as drug delivery carriers

Location: Strauss 2

Presenting Author: – Tokyo Medical University

Disease and therapy

10:00 – 10:30 CET

Coffee break

Location: Hall C

10:30 – 11:15 CET

Plenary 3: Exosomes as critical mediators of cell migration
Chair: Metka Lenassi
Co-Chair: Mario Gimona

Location: Plenary - Hall C

Presenter: – Vanderbilt University

11:15 – 11:30 CET

Featured Abstract: Non-lytic and active emission of cellular fragments carrying whole genome DNA during cancer cell migration

Location: Plenary - Hall C

Presenting Author: – Cancer Research Program, Research Institute of the McGill University Health Centre, Montreal, QC, Canada

EV sources and basic biology

11:30 – 11:45 CET

Featured Abstract: Syntenin controls extracellular vesicle-induced tumor migration by regulating the expression of adhesion proteins on small extracellular vesicles

Presenting Author: – University of Muenster, Dept. of Medicine A, Muenster, Germany

EV sources and basic biology

11:45 – 11:50 CET

Sponsor presentation: Particle Metrix

Location: Plenary - Hall C

11:50 – 11:55 CET

Sponsor presentation: NanoFCM

Location: Plenary - Hall C

11:55 – 12:00 CET

Sponsor presentation: Exokeryx

Location: Plenary - Hall C

12:00 – 13:30 CET

Lunch break

Location: Hall C

12:30 – 13:30 CET

Mixed Format: Meet the Editors Session

Location: VIP Lounge C

Moderator: – Krefting Research Centre, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

Moderator: – Victoria University, Melbourne, Australia

12:30 – 13:30 CET

Sponsor lunch: Everest Biolabs

Location: Stolz 1

12:30 – 13:30 CET

Sponsor lunch: Fujifilm Wako

Location: Stolz 2

12:30 – 13:30 CET

Sponsor lunch: HansaBioMed Life Sciences

Location: Schubert 1-3

12:30 – 13:30 CET

Sponsor lunch: Unchained Labs

Location: Schubert 4-6

12:30 – 14:30 CET

Poster Session 2 - Saturday Session Two Posters

14:30 – 15:00 CET

OS21.0 - EVs in Immune Suppression and Tumor Progression

Location: Strauss 2

Presenter: – University of Pennsylvania

Disease and therapy

15:00 – 15:15 CET

OS21.1 - A CD21 and phosphatidylserine-targeting fusion protein binds extracellular vesicles, targets them to B cells and potentiates their T-cell immunogenicity

Location: Strauss 2

Presenting Author: – Karolinska Institutet

Disease and therapy

15:15 – 15:30 CET

OS21.2 - Targeted exosomal delivery of PD-L1 siRNA in lung tumor immunotherapy

Location: Strauss 2

Presenting Author: – Brown Cancer Center and Department of Medicine, University of Louisville, Louisville, KY 40202, USA.

Disease and therapy

15:30 – 15:45 CET

OS21.3 - Mechanisms and functions of CSF1 association to extracellular vesicles in anti-tumor immune responses

Location: Strauss 2

Presenting Author: – Institut Curie Research center, INSERM U932, PSL Research University, Paris, France

Disease and therapy

15:45 – 16:00 CET

OS21.4 - Distinct role of large oncosomes in modulating bone marrow microenvironment and promoting metastasis through immune reprogramming in cancer progression

Location: Strauss 2

Presenting Author: – Cedars-Sinai Medical Center

Disease and therapy

14:30 – 15:00 CET

OS22.0 - Through the looking glass: tracking EVs in vivo

Location: Lehar 3-4

Presenter: – Faculty of Science, Utrecht University

Technologies and methods

15:00 – 15:15 CET

OS22.1 - Manipulation of Tumor Extracellular vesicles biodistribution and uptake in vivo by a cell-surface “EV-Trap”

Location: Lehar 3-4

Presenter: – Inserm U1307

Technologies and methods

15:15 – 15:30 CET

OS22.2 - Multiplexed isotopically enriched tellurium-based labeling of the EV proteome (MULTI-TeLEV) allows high-dimensional single-cell profiling of EV uptake from six different EV sources in parallel

Location: Lehar 3-4

Presenting Author: – Department I of Internal Medicine, Faculty of Medicine, University of Cologne, University Hospital Cologne, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, Center for Molecular Medicine Cologne, CECAD Center of Excellence on Cellular Stress Responses in Aging-Associated Diseases, Cologne, Germany

Technologies and methods

15:30 – 15:45 CET

OS22.3 - EVAnalyzer2: Moving from in vitro to in vivo high content single vesicle imaging for quantitative serum and tissue pharmacokinetics of extracellular vesicles using C++ and artificial intelligence-based image analysis.

Location: Lehar 3-4

Presenting Author: – Paris Lodron University of Salzburg, Salzburg, Austria and Ludwig Boltzmann Institute for Nanovesicular Precision Medicine, University of Salzburg, Austria

Technologies and methods

15:45 – 16:00 CET

OS22.4 - The making of bi-specific extracellular vesicles for targeted tissue-specific delivery

Location: Lehar 3-4

Presenting Author: – Ludwig Boltzmann Institute for Traumatology

Technologies and methods

14:30 – 15:00 CET

OS23.0 - EVs in periphery-brain communication

Location: Lehar 1-2

Presenter: – Flemish Institute for Biotechnology - Ghent University

Physiology and pathology

15:00 – 15:15 CET

OS23.1 - Exploring vitreous humor-derived extracellular vesicles as a window into CNS neurodegenerative and neuroinflammatory processes

Location: Lehar 1-2

Presenting Author: – KU Leuven

Physiology and pathology

15:15 – 15:30 CET

OS23.2 - Neuronal extracellular vesicles carrying APOE downregulate filament actin polymerization signaling to inhibit synapse formation in Alzheimer's Disease

Location: Lehar 1-2

Presenting Author: – Seventh Affiliated Hospital, Sun Yat-sen University

Physiology and pathology

15:30 – 15:45 CET

OS23.3 - Microglial extracellular vesicles promote synaptic pruning via C1q deposition at the synapse

Location: Lehar 1-2

Presenter: – CNR Institute of Neuroscience

Physiology and pathology

15:45 – 16:00 CET

OS23.4 - Extracellular vesicles modulate the amyloid β aggregation in Alzheimer’s disease via surface-expressed prion protein.

Location: Lehar 1-2

Presenting Author: – Institute of Neuropathology, University medical center Hamburg-Eppendorf

Physiology and pathology

14:30 – 15:00 CET

OS24.0 - EVs in cross-species Interactions: biology & applications

Location: Strauss 1

Presenter: – University of Edinburgh

Physiology and pathology

15:00 – 15:15 CET

OS24.1 - Planarian EVs: efficient transporters of RNAi fragments and other biomolecules

Location: Strauss 1

Presenting Author: – Stowers Institute

EV sources and basic biology

15:15 – 15:30 CET

OS24.2 - Pomegranate-derived nanovesicles as a promising therapy for inflammatory diseases: evidence from mouse models of acute pancreatitis and atopic dermatitis.

Location: Strauss 1

Presenting Author: – Universitat de Valencia

EV sources and basic biology

15:30 – 15:45 CET

OS24.3 - Microalgae-derived extracellular vesicles as multifunctional cosmetic ingredients against oxidative- and UVB-related damages

Location: Strauss 1

Presenting Author: – Institute of Biophysics - National Research Council of Italy

Physiology and pathology

15:45 – 16:00 CET

OS24.4 - The Sdp-SH3b2 domain contained in extracellular vesicles from the probiotic Lactobacillus johnsonii N6.2 inhibit murine norovirus replication

Location: Strauss 1

Presenting Author: – University of Florida

Physiology and pathology

16:00 – 16:30 CET

Coffee break

Location: Hall C

16:30 – 17:30 CET

General Assembly

Location: Plenary - Hall C

17:45 – 18:45 CET

Satellite Meeting: EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

Location: Stolz 1

Moderator: – Laboratory of Experimental Cancer Research, Ghent University, Ghent, Belgium

17:45 – 19:15 CET

Satellite Meeting: EV Pub Quiz by GSEV

Location: Schubert 4-6

17:45 – 19:15 CET

Satellite Meeting: 1st Symposium on Plant Extracellular Vesicles

Location: Lehar 3-4

Moderator: – Institute of Biosciences and Bioresources (IBBR) National council research (CNR), Naples, Italy

17:45 – 19:15 CET

Satellite Meeting: Blood Task Force Meeting

Location: VIP C Lounge

Moderator: – Mayo Clinic

Moderator: – Toronto General Hospital Research Institute, University Health Network

17:45 – 19:15 CET

Satellite Meeting: EVs in Aging and Regeneration

Location: Stolz 2

Moderator: – Biomaterials and Stem-Cell Based Therapeutics group, CNC- Center for Neuroscience and Cell Biology, University of Coimbra, Portugal

Moderator: – Ludwig Boltzmann Institute for Traumatology, the research center in cooperation with AUVA, Austria

17:45 – 19:15 CET

Satellite Meeting: GUSEV Special Interest Group Session - Roadblocks to EV Biomarker Translation

Location: Schubert 1-3

Moderator: – Ottawa Hospital Research Institute, Ottawa, Ontario, Canada

17:45 – 19:15 CET

Satellite Meeting: ISEV/ISCT Joint Session: Impact of donor, tissue and cell heterogeniety on the functionality of MSC-sEVs

Location: Lehar 1-2

Moderator: – Institute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

17:45 – 19:15 CET

Satellite Meeting: SIG-EViNS social: Extracellular Vesicles in Nervous Systems

Location: Strauss 1

Moderator: – Institute of Biology Paris-Seine (IBPS), Sorbonne University, CNRS UMR 8256, ERL INSERM U1164

17:45 – 19:15 CET

Satellite Meeting: SNEV-Industry on EVs: transition from academia, professional track, and challenges

Location: Strauss 2

Moderator: – Laboratory for extracellular vesicles research, Department of human genetics, KU Leuven, Leuven, Belgium