Mixed Format: Trauma and EVs

Extracellular vesicles (EVs) have emerged as powerful mediators of tissue repair and regeneration in physical trauma and injury. Preclinical studies demonstrate that EVs can modulate inflammation, promote angiogenesis, and enhance the proliferation and differentiation of progenitor cells, accelerating wound healing and tissue regeneration. Their ability to transfer bioactive molecules makes them attractive candidates for regenerative therapies in traumatology, including bone fractures, muscle injuries, and nerve damage. Moreover, EVs carry biomarkers that reflect the state of injured tissues, offering diagnostic and prognostic value for monitoring recovery. Engineered EVs further enhance therapeutic potential by improving stability, targeting specificity, and payload delivery. Here we will discuss progress made in this field.

This symposium is supported by AUVA.