UMC Utrecht
Utrecht, Utrecht, Netherlands
Sander A.A. Kooijmans works as a postdoctoral fellow in the CDL Research Nanomedicine group at the University Medical Center Utrecht, the Netherlands. In 2011 he started his PhD under supervision of prof. dr. Raymond Schiffelers in the same group, where he focused on engineering of extracellular vesicles (EVs) for drug delivery purposes. During his PhD, he published on the caveats associated with electroporation as a method for loading of exogenous nucleic acids in EVs, and described various ways to modify the surface of EVs with targeting ligands and 'stealth' properties to improve their circulation time. After obtaining his PhD in 2016, he moved to the Bioindustry Park Silvano Fumero in Turin, Italy, where he studied functionality of stem-cell derived EVs in the laboratory of prof. dr. Giovanni Camussi. In 2017 he returned to the Schiffelers lab in the University Medical Center Utrecht, where he swtiched gears and started to work on the design and development of state-of-the-art lipid nanoparticles for mRNA-based cancer immunotherapy. In the meanwhile, he remained involved in the EV field and now focuses on the capacity of various EV subpopulations to transfer cargo to recipient cells.
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OT05.4 - An engineered siRNA backbone improves siRNA delivery via extracellular vesicles
Thursday, April 24, 2025
15:45 – 16:00 CET